EGI-InSPIRE (Integrated Sustainable Pan-European Infrastructure for Researchers in Europe) is co-funded by the European Commission. It was launched on 1 May 2010 as a result of the collaboration of more than 100 institutions and 40 countries. These institutions include 37 National Grid Initiatives (NGIs), two European Intergovernmental Research Organisations (EIROs) and eight members from the Asia-Pacific region.

During the third phase of the EGEE project (EGEE-III, which was completed in late April 2010) migration took place from a Grid infrastructure model, based on an EU project developed during the first two phases of the EGEE project, to a model based on the federation of National Grid Infrastructures (NGIs).

The mission of the EGI-InSPIRE project is to establish a sustainable and reliable European Grid Infrastructure (EGI) to meet the needs of today's European scientists and their international partners for large scale data analysis. For this purpose, it uses Grid infrastructure providers from Europe and the rest of the world, and the new Distributed Computing Infrastructure technology (DCIs) now being developed.

EGI-InSPIRE will include the needs of users and provide support to currently identified research communities (e.g., high energy physics, astronomy, biotechnology) and those which may arise in the future.